Osteoarthritis (OA) is a progressive joint disease in dogs that causes chronic pain, reduced mobility, and decreased quality of life. While conventional treatments focus on symptom relief, regenerative therapies such as platelet-rich plasma (PRP) injections have attracted attention for their potential to modulate inflammation and promote tissue repair.
A 2025 study published in the Australian Veterinary Journal critically appraised existing research on the effectiveness of intra-articular PRP injections compared with placebo in improving clinical outcomes for canine OA. The review included findings from seven studies assessing changes in lameness and pain.
Results showed that the current evidence base is weak, with no consistent or substantial improvements in pain reduction or mobility restoration across the studies. The authors noted methodological limitations, including small sample sizes and lack of standardised protocols, which make it difficult to draw definitive conclusions on PRP’s efficacy.
The study emphasises that large, randomised, blinded controlled clinical trials are necessary to properly evaluate the therapeutic potential of PRP in managing canine osteoarthritis.
Source: Cai, X., & Zaki, S., Australian Veterinary Journal, Published July 21, 2025. https://doi.org/10.1111/avj.14456
